{"id":13096,"date":"2024-06-07T13:55:20","date_gmt":"2024-06-07T13:55:20","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13096"},"modified":"2024-07-08T14:00:23","modified_gmt":"2024-07-08T14:00:23","slug":"nirmatrelvir-ritonavir-and-symptoms-in-adults-with-postacute-sequelae-of-sars-cov-2-infection","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/nirmatrelvir-ritonavir-and-symptoms-in-adults-with-postacute-sequelae-of-sars-cov-2-infection\/","title":{"rendered":"Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13096\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Linda N.\u00a0Geng et al.<\/p>\n<p>Source Jamanetwork<\/p>\n<p><span class=\"heading-text thm-col h3 cb section-type-keyPoints decorated-hed sb-sc \">Key Points<\/span><\/p>\n<p><strong>Question<\/strong>\u00a0\u00a0What is the efficacy of 15 days of nirmatrelvir-ritonavir for improving select symptoms of postacute sequelae of SARS-CoV-2 infection (PASC)?<\/p>\n<p><strong>Findings<\/strong>\u00a0\u00a0This randomized clinical trial including 155 participants with PASC symptoms (\u22653 months\u2019 duration) found that a 15-day course of nirmatrelvir-ritonavir in a mostly vaccinated study cohort was generally safe, but did not show significant benefit in improving fatigue, brain fog, body aches, cardiovascular symptoms, shortness of breath, or gastrointestinal symptoms.<\/p>\n<p><strong>Meaning<\/strong>\u00a0\u00a0These findings indicate that further studies are needed to determine the role of antivirals in the treatment of PASC.<\/p>\n<p>Read more <a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2819901\">https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2819901<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Linda N.\u00a0Geng et al. Source Jamanetwork Key Points Question\u00a0\u00a0What is the efficacy of 15 days of nirmatrelvir-ritonavir for improving select symptoms of postacute sequelae of SARS-CoV-2 infection (PASC)? Findings\u00a0\u00a0This randomized clinical trial including 155 participants with PASC symptoms (\u22653 months\u2019 duration) found that a 15-day course of nirmatrelvir-ritonavir in a mostly vaccinated study cohort [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2613,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90],"tags":[],"class_list":["post-13096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13096","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13096"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13096\/revisions"}],"predecessor-version":[{"id":13097,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13096\/revisions\/13097"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/2613"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13096"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13096"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13096"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}