{"id":13204,"date":"2024-06-25T14:02:28","date_gmt":"2024-06-25T14:02:28","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13204"},"modified":"2024-07-12T14:04:45","modified_gmt":"2024-07-12T14:04:45","slug":"short-and-long-term-neuropsychiatric-outcomes-in-long-covid-in-south-korea-and-japan","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/short-and-long-term-neuropsychiatric-outcomes-in-long-covid-in-south-korea-and-japan\/","title":{"rendered":"Short- and long-term neuropsychiatric outcomes in long COVID in South Korea and Japan"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13204\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Sunyoung Kim et al.<\/p>\n<p>Source Nature<\/p>\n<h2 id=\"Abs1\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\">Abstract<\/h2>\n<div id=\"Abs1-content\" class=\"c-article-section__content\">\n<p>We investigated whether SARS-CoV-2 infection is associated with short- and long-term neuropsychiatric sequelae. We used population-based cohorts from the Korean nationwide cohort (discovery;\u00a0<i>n<\/i>\u2009=\u200910,027,506) and the Japanese claims-based cohort (validation;\u00a0<i>n<\/i>\u2009=\u200912,218,680) to estimate the short-term (&lt;30 days) and long-term (\u226530 days) risks of neuropsychiatric outcomes after SARS-CoV-2 infection compared with general population groups or external comparators (people with another respiratory infection). Using exposure-driven propensity score matching, we found that both the short- and long-term risks of developing neuropsychiatric sequelae were elevated in the discovery cohort compared with the general population and those with another respiratory infection. A range of conditions including Guillain-Barr\u00e9 syndrome, cognitive deficit, insomnia, anxiety disorder, encephalitis, ischaemic stroke and mood disorder exhibited a pronounced increase in long-term risk. Factors such as mild severity of COVID-19, increased vaccination against COVID-19 and heterologous vaccination were associated with reduced long-term risk of adverse neuropsychiatric outcomes. The time attenuation effect was the strongest during the first six months after SARS-CoV-2 infection, and this risk remained statistically significant for up to one year in Korea but beyond one year in Japan.<\/p>\n<p>Read more <a href=\"https:\/\/www.nature.com\/articles\/s41562-024-01895-8\">https:\/\/www.nature.com\/articles\/s41562-024-01895-8<\/a><\/p>\n<\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Sunyoung Kim et al. Source Nature Abstract We investigated whether SARS-CoV-2 infection is associated with short- and long-term neuropsychiatric sequelae. We used population-based cohorts from the Korean nationwide cohort (discovery;\u00a0n\u2009=\u200910,027,506) and the Japanese claims-based cohort (validation;\u00a0n\u2009=\u200912,218,680) to estimate the short-term (&lt;30 days) and long-term (\u226530 days) risks of neuropsychiatric outcomes after SARS-CoV-2 infection compared [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2687,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90,7],"tags":[],"class_list":["post-13204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19","category-news-commentary"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13204"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13204\/revisions"}],"predecessor-version":[{"id":13205,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13204\/revisions\/13205"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/2687"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13204"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}