{"id":13246,"date":"2024-04-22T14:29:42","date_gmt":"2024-04-22T14:29:42","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13246"},"modified":"2024-07-14T14:32:53","modified_gmt":"2024-07-14T14:32:53","slug":"the-persistence-of-sars-cov-2-in-tissues-and-its-association-with-long-covid-symptoms-a-cross-sectional-cohort-study-in-china","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/the-persistence-of-sars-cov-2-in-tissues-and-its-association-with-long-covid-symptoms-a-cross-sectional-cohort-study-in-china\/","title":{"rendered":"The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13246\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Wenting Zuo et al.<\/p>\n<p>Source The lancet<\/p>\n<h3>Background<\/h3>\n<div class=\"section-paragraph\">Growing evidence suggests that symptoms associated with post-COVID-19 condition (also known as long COVID) can affect multiple organs and systems in the human body, but their association with viral persistence is not clear. The aim of this study was to investigate the persistence of SARS-CoV-2 in diverse tissues at three timepoints following recovery from mild COVID-19, as well as its association with long COVID symptoms.<\/div>\n<div>\n<h3>Methods<\/h3>\n<div class=\"section-paragraph\">This single-centre, cross-sectional cohort study was done at China\u2013Japan Friendship Hospital in Beijing, China, following the omicron wave of COVID-19 in December, 2022. Individuals with mild COVID-19 confirmed by PCR or a lateral flow test scheduled to undergo gastroscopy, surgery, or chemotherapy, or scheduled for treatment in hospital for other reasons, at 1 month, 2 months, or 4 months after infection were enrolled in this study. Residual surgical samples, gastroscopy samples, and blood samples were collected approximately 1 month (18\u201333 days), 2 months (55\u201384 days), or 4 months (115\u2013134 days) after infection. SARS-CoV-2 was detected by digital droplet PCR and further confirmed through RNA in-situ hybridisation, immunofluorescence, and immunohistochemistry. Telephone follow-up was done at 4 months post-infection to assess the association between the persistence of SARS-CoV-2 RNA and long COVID symptoms.<\/div>\n<div><\/div>\n<div>Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/07\/PIIS1473309924001713-2.pdf\">click here<\/a><\/div>\n<\/div>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Wenting Zuo et al. Source The lancet Background Growing evidence suggests that symptoms associated with post-COVID-19 condition (also known as long COVID) can affect multiple organs and systems in the human body, but their association with viral persistence is not clear. The aim of this study was to investigate the persistence of SARS-CoV-2 in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2933,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[56,21],"tags":[],"class_list":["post-13246","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-based-research-in-western-medicine-clinical-practice","category-scientific-reports"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13246"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13246\/revisions"}],"predecessor-version":[{"id":13248,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13246\/revisions\/13248"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/2933"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13246"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}