{"id":13253,"date":"2024-07-03T13:27:41","date_gmt":"2024-07-03T13:27:41","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13253"},"modified":"2024-07-16T13:32:23","modified_gmt":"2024-07-16T13:32:23","slug":"tissue-based-t-cell-activation-and-viral-rna-persist-for-up-to-2-years-after-sars-cov-2-infection","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/tissue-based-t-cell-activation-and-viral-rna-persist-for-up-to-2-years-after-sars-cov-2-infection\/","title":{"rendered":"Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13253\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By MICHAEL J.\u00a0PELUSO et al.<\/p>\n<p>Source Science<\/p>\n<h2>Editor\u2019s summary<\/h2>\n<div role=\"paragraph\">The term \u201cLong Covid\u201d covers a diverse array of symptoms that an individual might experience weeks to years after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many drivers of Long Covid have been proposed, with supporting data for each. Here, Peluso\u00a0<i>et al.<\/i>\u00a0provide compelling evidence for two potential contributors: persistent SARS-CoV-2 and aberrant T cell activation. The authors used whole-body positron emission tomography imaging with a tracer that selectively tags activated T cells to show that those with Long Covid had certain tissues that were enriched for activated T cells in comparison with those without Long Covid. Moreover, because the gut was one of the sites of activated T cell enrichment, the authors analyzed gut biopsies from a subset of individuals with Long Covid.<\/div>\n<div role=\"paragraph\"><\/div>\n<div role=\"paragraph\">Read more <a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.adk3295\">https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.adk3295<\/a><\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By MICHAEL J.\u00a0PELUSO et al. Source Science Editor\u2019s summary The term \u201cLong Covid\u201d covers a diverse array of symptoms that an individual might experience weeks to years after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many drivers of Long Covid have been proposed, with supporting data for each. Here, Peluso\u00a0et al.\u00a0provide compelling evidence [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2670,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90,21,52],"tags":[],"class_list":["post-13253","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13253"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13253\/revisions"}],"predecessor-version":[{"id":13254,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13253\/revisions\/13254"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/2670"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13253"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}