{"id":13292,"date":"2024-07-04T14:10:34","date_gmt":"2024-07-04T14:10:34","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13292"},"modified":"2024-07-18T14:17:26","modified_gmt":"2024-07-18T14:17:26","slug":"impaired-metal-perception-and-regulation-of-associated-human-foliate-papillae-tongue-transcriptome-in-long-covid-19","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/impaired-metal-perception-and-regulation-of-associated-human-foliate-papillae-tongue-transcriptome-in-long-covid-19\/","title":{"rendered":"Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13292\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Barbara Danzer et al.<\/p>\n<p>Source Nature<\/p>\n<h2 id=\"Abs1\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\">Abstract<\/h2>\n<div id=\"Abs1-content\" class=\"c-article-section__content\">\n<p>Chemosensory impairment is an outstanding symptom of SARS-CoV-2 infections. We hypothesized that measured sensory impairments are accompanied by transcriptomic changes in the foliate papillae area of the tongue. Hospital personnel with known SARS-CoV-2 immunoglobulin G (IgG) status completed questionnaires on sensory perception (<i>n<\/i>\u2009=\u2009158). A subcohort of\u00a0<i>n<\/i>\u2009=\u2009141 participated in forced choice taste tests, and\u00a0<i>n<\/i>\u2009=\u200943 participants consented to donate tongue swabs of the foliate papillae area for whole transcriptome analysis. The study included four groups of participants differing in IgG levels (\u2265\u200910 AU\/mL\u2009=\u2009IgG<sup>+<\/sup>;\u2009&lt;\u200910 AU\/mL\u2009=\u2009IgG<sup>&#8211;<\/sup>) and self-reported sensory impairment (SSI<sup>\u00b1<\/sup>). IgG<sup>+<\/sup>\u00a0subjects not detecting metallic taste had higher IgG<sup>+<\/sup>\u00a0levels than IgG<sup>+<\/sup>\u00a0participants detecting iron gluconate (<i>p<\/i>\u2009=\u20090.03).<\/p>\n<p>Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/07\/s41598-024-66079-w.pdf\">click here<\/a><\/p>\n<\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Barbara Danzer et al. Source Nature Abstract Chemosensory impairment is an outstanding symptom of SARS-CoV-2 infections. We hypothesized that measured sensory impairments are accompanied by transcriptomic changes in the foliate papillae area of the tongue. Hospital personnel with known SARS-CoV-2 immunoglobulin G (IgG) status completed questionnaires on sensory perception (n\u2009=\u2009158). A subcohort of\u00a0n\u2009=\u2009141 participated [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":13294,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90,21,52],"tags":[],"class_list":["post-13292","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13292"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13292\/revisions"}],"predecessor-version":[{"id":13295,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13292\/revisions\/13295"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/13294"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13292"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}