{"id":13602,"date":"2024-05-21T14:38:13","date_gmt":"2024-05-21T14:38:13","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=13602"},"modified":"2024-08-01T14:40:47","modified_gmt":"2024-08-01T14:40:47","slug":"sars-cov-2-infection-exacerbates-the-cellular-pathology-of-parkinsons-disease-in-human-dopaminergic-neurons-and-a-mouse-model","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/sars-cov-2-infection-exacerbates-the-cellular-pathology-of-parkinsons-disease-in-human-dopaminergic-neurons-and-a-mouse-model\/","title":{"rendered":"SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson\u2019s disease in human dopaminergic neurons and a mouse model"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/13602\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Bina Lee et al.<\/p>\n<p>Source Cell<\/p>\n<h2 id=\"secsectitle0020\" class=\"top\" tabindex=\"-1\" data-left-hand-nav=\"Highlights\"><span class=\"top__text\">Highlights<\/span><\/h2>\n<div class=\"section-paragraph\">\n<ul id=\"ulist0010\" class=\"ce-list--remove-bullets\">\n<li id=\"u0010\" class=\"ce-list--remove-bullets__list-item\"><span class=\"label\">\u2022<\/span>\n<div class=\"ce-list--remove-bullets__list-item__text\">SARS-CoV-2 infection via the nasal cavity spreads to the brain<\/div>\n<\/li>\n<li id=\"u0015\" class=\"ce-list--remove-bullets__list-item\"><span class=\"label\">\u2022<\/span>\n<div class=\"ce-list--remove-bullets__list-item__text\">Deterioration of Parkinson\u2019s disease molecular and cellular phenotype by SARS-CoV-2<\/div>\n<\/li>\n<li id=\"u0020\" class=\"ce-list--remove-bullets__list-item\"><span class=\"label\">\u2022<\/span>\n<div class=\"ce-list--remove-bullets__list-item__text\">SARS-CoV-2 worsens \u03b1-synuclein preformed-fibril-induced dopaminergic neuron death<\/div>\n<\/li>\n<li id=\"u0025\" class=\"ce-list--remove-bullets__list-item\"><span class=\"label\">\u2022<\/span>\n<div class=\"ce-list--remove-bullets__list-item__text\">SARS-CoV-2 triggers prolonged neuroinflammation for over 60 days in hACE2-Tg mice<\/div>\n<\/li>\n<\/ul>\n<p>Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/08\/1-s2.0-S2666379124002623-main.pdf\">click here<\/a><\/p>\n<\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Bina Lee et al. Source Cell Highlights \u2022 SARS-CoV-2 infection via the nasal cavity spreads to the brain \u2022 Deterioration of Parkinson\u2019s disease molecular and cellular phenotype by SARS-CoV-2 \u2022 SARS-CoV-2 worsens \u03b1-synuclein preformed-fibril-induced dopaminergic neuron death \u2022 SARS-CoV-2 triggers prolonged neuroinflammation for over 60 days in hACE2-Tg mice Read more click here<\/p>\n","protected":false},"author":1,"featured_media":13577,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[21,52],"tags":[],"class_list":["post-13602","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=13602"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13602\/revisions"}],"predecessor-version":[{"id":13604,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/13602\/revisions\/13604"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/13577"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=13602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=13602"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=13602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}