{"id":14018,"date":"2024-07-04T14:10:12","date_gmt":"2024-07-04T14:10:12","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=14018"},"modified":"2024-08-20T14:13:18","modified_gmt":"2024-08-20T14:13:18","slug":"identification-of-sialic-acid-receptors-for-influenza-a-virus-in-snakes","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/identification-of-sialic-acid-receptors-for-influenza-a-virus-in-snakes\/","title":{"rendered":"Identification of sialic acid receptors for influenza A virus in snakes"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/14018\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By <span class=\"given-name\">Yasmin C.<\/span>\u00a0<span class=\"text surname\">e Silva et al.<\/span><\/p>\n<p>Source sciencedirect<\/p>\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<div id=\"abssec0010\">\n<p id=\"abspara0010\">The\u00a0tissue tropism\u00a0and the wide host range of\u00a0influenza A viruses\u00a0are determined by the presence of\u00a0sialic acid\u00a0(SA) \u03b12,3-Gal and SA \u03b12,6-Gal receptors. Recent studies have shown that animals possessing both receptors allow for the rearrangement and emergence of new viral strains of public health importance. This study aimed to evaluate the expression and distribution of human and\u00a0avian influenza\u00a0A receptors in nine Neotropical snake species using\u00a0lectin\u00a0immunohistochemistry. We selected 17 snakes that were examined\u00a0<em>post mortem<\/em>\u00a0at the\u00a0Veterinary Pathology\u00a0Sector of the Universidade Federal de Minas Gerais between 2019 and 2023. Sections of nasal turbinate, trachea, lung, oral\u00a0mucosa, stomach and intestine were subjected to immunohistochemical analysis using the lectins\u00a0Maackia\u00a0amurensis\u00a0and\u00a0Sambucus nigra. This research detected, for the first time, co-expression of SA \u03b12,3-Gal and SA \u03b12,6-Gal receptors in the respiratory and digestive tracts of snakes, indicating the possible susceptibility of these species to\u00a0influenza A\u00a0virus of avian and human origin.<\/p>\n<p>Read more <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0021997524002652\">https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0021997524002652<\/a><\/p>\n<\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Yasmin C.\u00a0e Silva et al. Source sciencedirect Abstract The\u00a0tissue tropism\u00a0and the wide host range of\u00a0influenza A viruses\u00a0are determined by the presence of\u00a0sialic acid\u00a0(SA) \u03b12,3-Gal and SA \u03b12,6-Gal receptors. Recent studies have shown that animals possessing both receptors allow for the rearrangement and emergence of new viral strains of public health importance. This study aimed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14019,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[21,52],"tags":[],"class_list":["post-14018","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=14018"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14018\/revisions"}],"predecessor-version":[{"id":14020,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14018\/revisions\/14020"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/14019"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=14018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=14018"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=14018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}