{"id":14266,"date":"2024-08-16T08:28:49","date_gmt":"2024-08-16T08:28:49","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=14266"},"modified":"2024-08-29T08:34:33","modified_gmt":"2024-08-29T08:34:33","slug":"virological-characteristics-of-the-sars-cov-2-kp-3-1-1-variant","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/virological-characteristics-of-the-sars-cov-2-kp-3-1-1-variant\/","title":{"rendered":"Virological characteristics of the SARS-CoV-2 KP.3.1.1 variant"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/14266\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By <span class=\"authors\"><span role=\"list\"><span role=\"listitem\"><span class=\"dropBlock\">Yu Kaku<\/span><\/span><\/span><\/span> et al.<\/p>\n<p>Source The Lancet<\/p>\n<div>\n<div class=\"core-content-inner\">\n<section id=\"bodymatter\" data-extent=\"bodymatter\">\n<div class=\"core-container\">\n<div id=\"para10\" role=\"paragraph\">The SARS-CoV-2 JN.1 variant (BA.2.86.1.1), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted the previously predominant XBB lineages by the beginning of 2024.<span class=\"dropBlock reference-citations\"><sup>1<\/sup><\/span> Subsequently, JN.1 subvariants including KP.2 (JN.1.11.1.2) and KP.3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently (appendix pp 19\u201320).<span class=\"dropBlock reference-citations\"><sup>2<\/sup><\/span> Thereafter, JN.1 subvariants, such as LB.1 (JN.1.9.2.1), KP.2.3 (JN.1.11.1.2.3), and KP.3.1.1 (JN.1.11.1.3.1.1), which convergently acquired a deletion of serine at position 31 in S (S:S31del) in addition to the above substitutions, have emerged and have spread as of June 2024 (appendix pp 19\u201320). We recently reported the virological features of JN.1 subvariants including KP.2, KP.3, LB.1, and KP.2.3.<span class=\"dropBlock reference-citations\"><sup>2,3<\/sup><\/span> Here, we investigated the virological properties of KP.3.1.1.<\/div>\n<\/div>\n<div role=\"paragraph\"><\/div>\n<div role=\"paragraph\">Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/08\/PIIS147330992400505X.pdf\">click here<\/a><\/div>\n<div role=\"paragraph\"><\/div>\n<\/section>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Yu Kaku et al. Source The Lancet The SARS-CoV-2 JN.1 variant (BA.2.86.1.1), arising from BA.2.86.1 with spike protein (S) substitution S:L455S, outcompeted the previously predominant XBB lineages by the beginning of 2024.1 Subsequently, JN.1 subvariants including KP.2 (JN.1.11.1.2) and KP.3 (JN.1.11.1.3), which acquired additional S substitutions (eg, S:R346T, S:F456L, and S:Q493E) have emerged concurrently [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[21,52],"tags":[],"class_list":["post-14266","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=14266"}],"version-history":[{"count":2,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14266\/revisions"}],"predecessor-version":[{"id":14270,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14266\/revisions\/14270"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/14269"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=14266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=14266"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=14266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}