{"id":14583,"date":"2024-09-21T14:51:55","date_gmt":"2024-09-21T14:51:55","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=14583"},"modified":"2024-09-22T14:56:35","modified_gmt":"2024-09-22T14:56:35","slug":"epidemiology-and-drug-resistance-among-candida-pathogens-in-africa-candida-auris-could-now-be-leading-the-pack","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/epidemiology-and-drug-resistance-among-candida-pathogens-in-africa-candida-auris-could-now-be-leading-the-pack\/","title":{"rendered":"Epidemiology and drug resistance among Candida pathogens in Africa: Candida auris could now be leading the pack"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/14583\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Chibuike\u00a0Ibe et al.<\/p>\n<p>Source Lancet<\/p>\n<div id=\"p0010\" role=\"paragraph\">Globally, 1\u2009565\u2009000\u00a0people have invasive candidiasis every year. These individuals are mainly immunocompromised people, including critically ill patients in the intensive care unit, people receiving extended use of broad-spectrum antibiotics, and of late, individuals with complications of post-COVID-19 condition (also known as long COVID). Invasive candidiasis is often misdiagnosed and accounts for 995\u2009000\u00a0deaths (63\u00b76% of all cases) annually.<span class=\"dropBlock reference-citations\"><sup>1<\/sup><\/span>\u00a0As per estimates, Africa has a greater share of the invasive candidiasis burden than the rest of the world. These estimates are rough, and the paucity of accurate epidemiological data due to insufficient fungal diagnostics complicates efforts to accurately contextualise the disease.<span class=\"dropBlock reference-citations\"><sup>2<\/sup><\/span><\/div>\n<div id=\"p0015\" role=\"paragraph\">The\u00a0<i>Candida<\/i>\u00a0genus contains a mix of pathogens showing heterogeneous behaviour and unique pathogenic traits within the human host. For example,\u00a0<i>Candida glabrata<\/i>\u00a0commonly infects older individuals (\u226565\u00a0years), whereas\u00a0<i>Candida parapsilosis<\/i>\u00a0is frequently isolated from neonates and infants.\u00a0<i>Candida albicans<\/i>\u00a0is the most versatile of all\u00a0<i>Candida<\/i>\u00a0pathogens and can cause infection that affects multiple organs, including the lungs and brain. Although these species are not generally transmitted between hosts, a newly emerging species,\u00a0<i>Candida auris<\/i>, comprising six clades, causes large hospital outbreaks, changing the epidemiological landscape of invasive candidiasis (appendix p 1).<\/div>\n<p>&nbsp;<\/p>\n<p>Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/09\/PIIS2666524724002647.pdf\">click here<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Chibuike\u00a0Ibe et al. Source Lancet Globally, 1\u2009565\u2009000\u00a0people have invasive candidiasis every year. These individuals are mainly immunocompromised people, including critically ill patients in the intensive care unit, people receiving extended use of broad-spectrum antibiotics, and of late, individuals with complications of post-COVID-19 condition (also known as long COVID). Invasive candidiasis is often misdiagnosed and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14585,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90],"tags":[],"class_list":["post-14583","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=14583"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14583\/revisions"}],"predecessor-version":[{"id":14586,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14583\/revisions\/14586"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/14585"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=14583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=14583"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=14583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}