{"id":14843,"date":"2024-10-14T08:55:09","date_gmt":"2024-10-14T08:55:09","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=14843"},"modified":"2024-10-17T09:01:36","modified_gmt":"2024-10-17T09:01:36","slug":"perioperative-cardiovascular-risk-and-preventions-of-patients-with-post-covid-19-condition","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/perioperative-cardiovascular-risk-and-preventions-of-patients-with-post-covid-19-condition\/","title":{"rendered":"Perioperative cardiovascular risk and preventions of patients with post-COVID-19 condition"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/14843\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By <span class=\"authors\"><span role=\"list\"><span role=\"listitem\">Sixu Lai<\/span><\/span><\/span> et al.<\/p>\n<p>Source Cell<\/p>\n<p>COVID-19 has the potential to cause damage to the cardiovascular system through excessive inflammation and cytokine storm.<\/p>\n<p>SARS-CoV-2 may induce cardiovascular damage by stabilizing NFKBIZ, a kind of mRNA targets, to inhibit host cells and promote the production of more cytokines such as IL 6 and IL 8.<\/p>\n<p>COVID-19 could infect and replicate in macrophages and foam cells in the coronary vessels of patients, triggering excessive inflammatory response by inhibiting the levels of type I interferon and maintaining the long-term infection status of SARS-CoV-2.<\/p>\n<p>Even more, severe COVID-19 infection can cause persistent changes in the innate immune phenotype and epigenetic program of hematopoietic stem cells and progenitor cells.<\/p>\n<p>These changes can cause organ dysfunction and inflammation, which can be inherited by subsequent cells.<\/p>\n<p>An imaging report on multiple organs in patients with COVID-19 infection revealed that after 5 months of infection, over 30 % of patients had more than one organ abnormality.<\/p>\n<p>After 6 months of infection, over 60 % of patients had multi-organ function damage, with the most severe injuries occurring in the head and lungs.<\/p>\n<p>\u201cLong-term COVID-19\u201d is not caused by serious defects in one organ, but rather is a common result of multiple system abnormalities.<\/p>\n<p>&nbsp;<\/p>\n<p>Read more<a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/10\/1-s2.0-S2405844024153765-main.pdf\"> click here<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Sixu Lai et al. Source Cell COVID-19 has the potential to cause damage to the cardiovascular system through excessive inflammation and cytokine storm. SARS-CoV-2 may induce cardiovascular damage by stabilizing NFKBIZ, a kind of mRNA targets, to inhibit host cells and promote the production of more cytokines such as IL 6 and IL 8. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":14269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[90],"tags":[],"class_list":["post-14843","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-long-covid19"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=14843"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14843\/revisions"}],"predecessor-version":[{"id":14845,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/14843\/revisions\/14845"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/14269"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=14843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=14843"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=14843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}