{"id":15130,"date":"2024-11-07T08:08:24","date_gmt":"2024-11-07T08:08:24","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=15130"},"modified":"2024-11-20T08:15:07","modified_gmt":"2024-11-20T08:15:07","slug":"15130-2","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/15130-2\/","title":{"rendered":"The kinetics of SARS-CoV-2 infection based on a human challenge study"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/15130\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By <span class=\"authors\"><span role=\"list\"><span role=\"listitem\">Sarafa A. Iyaniwura et al. <\/span><\/span><\/span><\/p>\n<p>Source PNAS<\/p>\n<p>&nbsp;<\/p>\n<p>\u4efd\u5b50\u6230\u722d\uff0c\u9069\u8005\u751f\u5b58<\/p>\n<p>Key study used a SARS-CoV-2 human challenge dataset to model viral dynamics and immune responses.<\/p>\n<p>\u25b6\ufe0f It found that infectious virus increases sublinearly with total virus, suggesting the fraction of infectious particles declines.<\/p>\n<p>\u25b6\ufe0f Viral replication is extremely rapid, doubling every 2-3 hours early on.<\/p>\n<p>\u25b6\ufe0f Innate immunity limits viral growth initially, but wanes as infection is controlled.<\/p>\n<p>\u25b6\ufe0f Adaptive immunity, including antibodies and T cells, kicks in around 7-10 days and contributes to stepwise viral decline, though rebounds can occur as the innate response fades.<\/p>\n<p>HOW SARS-COV-2 INFECTS YOU ?<\/p>\n<p>&nbsp;<\/p>\n<p>Read more <a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/11\/iyaniwura-et-al-2024-the-kinetics-of-sars-cov-2-infection-based-on-a-human-challenge-study.pdf\">click here<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Sarafa A. Iyaniwura et al. Source PNAS &nbsp; \u4efd\u5b50\u6230\u722d\uff0c\u9069\u8005\u751f\u5b58 Key study used a SARS-CoV-2 human challenge dataset to model viral dynamics and immune responses. \u25b6\ufe0f It found that infectious virus increases sublinearly with total virus, suggesting the fraction of infectious particles declines. \u25b6\ufe0f Viral replication is extremely rapid, doubling every 2-3 hours early on. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15131,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[21,52],"tags":[],"class_list":["post-15130","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=15130"}],"version-history":[{"count":2,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15130\/revisions"}],"predecessor-version":[{"id":15134,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15130\/revisions\/15134"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/15131"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=15130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=15130"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=15130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}