{"id":15241,"date":"2024-12-16T08:55:06","date_gmt":"2024-12-16T08:55:06","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=15241"},"modified":"2024-12-17T09:29:15","modified_gmt":"2024-12-17T09:29:15","slug":"skipping-chest-wall-irradiation-after-mastectomy-in-intermediate-risk-breast-cancer","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/skipping-chest-wall-irradiation-after-mastectomy-in-intermediate-risk-breast-cancer\/","title":{"rendered":"Skipping Chest-Wall Irradiation After Mastectomy in Intermediate-Risk Breast Cancer"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/15241\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By Charles Bankhead<\/p>\n<p>Source Medpagetoday<\/p>\n<p>SAN ANTONIO &#8212; Postmastectomy chest-wall irradiation (CWI) for intermediate-risk breast cancer had no impact on long-term survival, results of a large British study showed.<\/p>\n<p>After a median follow-up of 9.6 years, irradiated patients had a 10-year overall survival (OS) of 81.4% versus 82% for those who had no CWI. CWI led to a &#8220;clinically insignificant&#8221; reduction in chest-wall recurrence from 2.5% to 1.1%, representing a total of 29 recurrences among more than 1,600 women.<\/p>\n<p>The results indicate that most women with intermediate-risk breast cancer can safely avoid CWI following mastectomy, said Ian Kunkler, MB BChir, of the University of Edinburgh in Scotland, at the San Antonio Breast Cancer Symposiumopens in a new tab or window (SABCS).<\/p>\n<p>&#8220;Chest-wall irradiation did not improve 10-year overall survival, and it results in a clinically insignificant reduction in chest-wall recurrence of less than 2%,&#8221; Kunkler said during a press briefing. &#8220;It has no impact on disease-free or metastasis-free survival [DFS\/MFS], and we believe these findings are consistent with incremental changes and improvements in multidisciplinary care [for breast cancer] over the period of the trial.&#8221;<\/p>\n<p>&#8220;Adjuvant, chest-wall irradiation should be omitted in most patients meeting the eligibility of the SUPREMO opens in a new tab or windowtrial,&#8221; he stated.<\/p>\n<p>&nbsp;<\/p>\n<p>Read more <a href=\"https:\/\/www.medpagetoday.com\/meetingcoverage\/sabcs\/113417\">https:\/\/www.medpagetoday.com\/meetingcoverage\/sabcs\/113417<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By Charles Bankhead Source Medpagetoday SAN ANTONIO &#8212; Postmastectomy chest-wall irradiation (CWI) for intermediate-risk breast cancer had no impact on long-term survival, results of a large British study showed. After a median follow-up of 9.6 years, irradiated patients had a 10-year overall survival (OS) of 81.4% versus 82% for those who had no CWI. CWI [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15242,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[47,129,33],"tags":[],"class_list":["post-15241","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-cancer-pages","category-western-medicine"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=15241"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15241\/revisions"}],"predecessor-version":[{"id":15243,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15241\/revisions\/15243"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/15242"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=15241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=15241"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=15241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}