{"id":15325,"date":"2025-01-06T07:13:12","date_gmt":"2025-01-06T07:13:12","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=15325"},"modified":"2025-01-08T07:16:54","modified_gmt":"2025-01-08T07:16:54","slug":"architects-of-infection-a-structural-overview-of-sars-related-coronavirus-spike-glycoproteins","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/architects-of-infection-a-structural-overview-of-sars-related-coronavirus-spike-glycoproteins\/","title":{"rendered":"Architects of infection: A structural overview of SARS-related coronavirus spike glycoproteins"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"http:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/15325\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>By\u00a0<span class=\"button-link-text-container\"><span class=\"button-link-text\"><span class=\"react-xocs-alternative-link\"><span class=\"given-name\">Francesca R.<\/span> <span class=\"text surname\">Hills<\/span> <\/span><\/span><\/span>et al.<\/p>\n<p>Source: sciencedirect<\/p>\n<p>The SARS-CoV-2 spike protein tends to adopt an &#8220;open&#8221; shape that is more primed for binding and entering human cells. In contrast, the spikes of animal coronaviruses are often in a &#8220;closed&#8221; shape, which is better for infecting their natural bat hosts but less efficient for human infection.<\/p>\n<p>This structural difference is a key reason why SARS-CoV-2 was able to spread so effectively in the human population, causing a global pandemic.<\/p>\n<p>Read more<a href=\"https:\/\/www.drknowhk.org\/wp-content\/uploads\/2025\/01\/1-s20-S0042682224004070-main_250107_220230.pdf\"> click here<\/a><\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002By\u00a0Francesca R. Hills et al. Source: sciencedirect The SARS-CoV-2 spike protein tends to adopt an &#8220;open&#8221; shape that is more primed for binding and entering human cells. In contrast, the spikes of animal coronaviruses are often in a &#8220;closed&#8221; shape, which is better for infecting their natural bat hosts but less efficient for human infection. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15327,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[21,52],"tags":[],"class_list":["post-15325","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-reports","category-virology-pathophysiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=15325"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15325\/revisions"}],"predecessor-version":[{"id":15328,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/15325\/revisions\/15328"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/15327"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=15325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=15325"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=15325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}