{"id":6195,"date":"2020-02-22T15:08:46","date_gmt":"2020-02-22T15:08:46","guid":{"rendered":"http:\/\/www.drknowhk.org\/?p=6195"},"modified":"2024-03-13T10:17:04","modified_gmt":"2024-03-13T10:17:04","slug":"%e4%b8%ad%e6%96%87-2019-ncov-transmission-through-the-ocular-surface-must-not-be-ignored","status":"publish","type":"post","link":"http:\/\/www.drknowhk.org\/mo\/%e4%b8%ad%e6%96%87-2019-ncov-transmission-through-the-ocular-surface-must-not-be-ignored\/","title":{"rendered":"2019-nCoV transmission through the ocular surface must not be ignored"},"content":{"rendered":"<p><\/p>\n<div class=\"section-paragraph\">Chaolin Huang and colleagues<a id=\"back-bib1\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib1\" data-db-target-for=\"bib1-d1721187e93\" aria-expanded=\"false\" aria-controls=\"bib1\">1 <\/a>reported the epidemiology, symptoms, and treatment of patients infected by the 2019 novel coronavirus (2019-nCoV) in Wuhan, China. As ophthalmologists, we believe that transmission of 2019-nCoV through the eyes was ignored.<\/div>\n<p>&nbsp;<\/p>\n<div class=\"section-paragraph\">On Jan 22, Guangfa Wang, a member of the national expert panel on pneumonia, reported that he was infected by 2019-nCoV during the inspection in Wuhan.<a id=\"back-bib2\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib2\" data-db-target-for=\"bib2-d1721187e99\" aria-expanded=\"false\" aria-controls=\"bib2\">2 <\/a>He wore an N95 mask but did not wear anything to protect his eyes. Several days before the onset of pneumonia, Wang complained of redness of the eyes. Unprotected exposure of the eyes to 2019-nCoV in the Wuhan Fever Clinic might have allowed the virus to infect the body.<a id=\"back-bib2\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib2\" data-db-target-for=\"bib2-d1721187e103\" aria-expanded=\"false\" aria-controls=\"bib2\">2<\/a><\/div>\n<p>&nbsp;<\/p>\n<div>\n<div class=\"section-paragraph\">Infectious droplets and body fluids can easily contaminate the human conjunctival epithelium.<a id=\"back-bib3\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib3\" data-db-target-for=\"bib3-d1721187e108\" aria-expanded=\"false\" aria-controls=\"bib3\">3<\/a> Respiratory viruses are capable of inducing ocular complications in infected patients, which then leads to respiratory infection.<a id=\"back-bib4\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib4\" data-db-target-for=\"bib4-d1721187e112\" aria-expanded=\"false\" aria-controls=\"bib4\">4<\/a><\/div>\n<p>&nbsp;<\/p>\n<div class=\"section-paragraph\">Severe acute respiratory syndrome coronavirus (SARS-CoV) is predominantly transmitted through direct or indirect contact with mucous membranes in the eyes, mouth, or nose.<a id=\"back-bib5\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib5\" data-db-target-for=\"bib5-d1721187e116\" aria-expanded=\"false\" aria-controls=\"bib5\">5<\/a> The fact that exposed mucous membranes and unprotected eyes increased the risk of SARS-CoV transmission<a id=\"back-bib4\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib4\" data-db-target-for=\"bib4-d1721187e120\" aria-expanded=\"false\" aria-controls=\"bib4\">4<\/a>\u00a0suggests that exposure of unprotected eyes to 2019-nCoV could cause acute respiratory infection.<\/div>\n<p>&nbsp;<\/p>\n<div class=\"section-paragraph\">Thus, Huang and colleagues<a id=\"back-bib1\" class=\"reference-citations__ctrl\" style=\"vertical-align: super;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext#bib1\" data-db-target-for=\"bib1-d1721187e126\" aria-expanded=\"false\" aria-controls=\"bib1\">1<\/a>\u00a0should have analysed conjunctival scrapings from both confirmed and suspected 2019-nCoV cases during the onset of symptoms. The respiratory tract is probably not the only transmission route for 2019-nCoV, and all ophthalmologists examining suspected cases should wear protective eyewear.<\/div>\n<p>&nbsp;<\/p>\n<div class=\"section-paragraph\">We declare no competing interests.<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<div>\n<h2 id=\"seccestitle10\" class=\"top\" data-left-hand-nav=\"References\"><span class=\"top__text\">References<\/span><\/h2>\n<p><span class=\"refLabel\">1. <\/span>Huang C , Wang YM , Li X , et al.<\/p>\n<div class=\"ref__title\"><strong>Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.<\/strong><\/div>\n<p><span class=\"ref__series\"><i>Lancet.<\/i><span class=\"ref__seriesDate\">2020;\u00a0<\/span>(<span class=\"refComment\">published online Jan 24. https:\/\/doi.org\/10.1016\/S0140-6736(20)30183-5.<\/span>)<\/span><\/p>\n<\/div>\n<p><span class=\"refLabel\">2. <\/span>Dai X<\/p>\n<div class=\"ref__title\"><strong>Peking University Hospital Wang Guangfa disclosed treatment status on Weibo and suspected infection without wearing goggles.<\/strong><\/div>\n<div class=\"citation-host\">\n<p><a href=\"http:\/\/www.bjnews.com.cn\/news\/2020\/01\/23\/678189.html\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.bjnews.com.cn\/news\/2020\/01\/23\/678189.html<\/a><\/p>\n<div>Date:\u00a0Jan 22, 2020<\/div>\n<div>Date accessed:\u00a0January 24, 2020<\/div>\n<\/div>\n<div><\/div>\n<div>\n<p><span class=\"refLabel\">3. <\/span>Olofsson S, Kumlin U, Dimock K, Arnberg N<\/p>\n<div class=\"ref__title\"><strong>Avian influenza and sialic acid receptors: more than meets the eye?.<\/strong><\/div>\n<p><span class=\"ref__series\"><i>Lancet Infect Dis.<\/i>\u00a0<span class=\"ref__seriesDate\">2005;\u00a0<\/span><span class=\"ref__seriesVolume\">5<\/span><\/span>:\u00a0<span class=\"ref__seriesPages\">184-188<\/span><\/p>\n<\/div>\n<div><\/div>\n<div>\n<p><span class=\"refLabel\">4. <\/span>Belser JA ,Rota PA, Tumpey TM<\/p>\n<div class=\"ref__title\"><strong>Ocular tropism of respiratory viruses.<\/strong><\/div>\n<p><span class=\"ref__series\"><i>Microbiol Mol Biol Rev.<\/i>\u00a0<span class=\"ref__seriesDate\">2013;\u00a0<\/span><span class=\"ref__seriesVolume\">77<\/span><\/span>:\u00a0<span class=\"ref__seriesPages\">144-156<\/span><\/p>\n<\/div>\n<div><\/div>\n<div>\n<p><span class=\"refLabel\">5. <\/span>Peiris JS, Yuen KY, Osterhaus AD, Stohr K<\/p>\n<div class=\"ref__title\"><strong>The severe acute respiratory syndrome.<\/strong><\/div>\n<p><span class=\"ref__series\"><i>N Engl J Med.<\/i>\u00a0<span class=\"ref__seriesDate\">2003;\u00a0<\/span><span class=\"ref__seriesVolume\">349<\/span><\/span>:\u00a0<span class=\"ref__seriesPages\">2431-2441<\/span><\/p>\n<\/div>\n<p>\u985e\u578b: \u6587\u7ae0<br \/>\n\u4f5c\u8005: Cheng-wei Lu et al.<br \/>\n\u51fa\u8655: The Lancet<br \/>\n\u9023\u7d50: <a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext\">https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30313-5\/fulltext<\/a><br \/>\n<\/p>","protected":false},"excerpt":{"rendered":"<p>Chaolin Huang and colleagues reported the epidemiology, symptoms, and treatment of patients infected by the 2019 novel coronavirus (2019-nCoV) in Wuhan, China. As ophthalmologists, we believe that transmission of 2019-nCoV through the eyes&#8230;&#8230;<\/p>\n","protected":false},"author":1,"featured_media":2487,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[51],"tags":[],"class_list":["post-6195","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-manifestations-epidemiology"],"_links":{"self":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/6195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=6195"}],"version-history":[{"count":1,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/6195\/revisions"}],"predecessor-version":[{"id":6196,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/6195\/revisions\/6196"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/2487"}],"wp:attachment":[{"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=6195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=6195"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=6195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}