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The new coronavirus pneumonia, named COVID-19 by the World Health Organization, has become a pandemic.It is highly pathogenic and reproduces quickly. There are currently no specific drugs to prevent the reproductionand spread of COVID-19. Some traditional Chinese medicines, especially the Lung Cleansing and DetoxifyingDecoction (Qing Fei Pai Du Tang), have shown therapeutic effects on mild and ordinary COVID-19 patients.Polysaccharides are important ingredients in this decoction. This review summarizes the potential pharmaco-logical activities of polysaccharides isolated by hot water extraction from Lung Cleansing and DetoxifyingDecoction, which is consistent with its production method, to provide the theoretical basis for ongoing researchon its application