{"id":12829,"date":"2024-05-03T14:21:15","date_gmt":"2024-05-03T14:21:15","guid":{"rendered":"https:\/\/www.drknowhk.org\/?p=12829"},"modified":"2024-06-26T14:25:16","modified_gmt":"2024-06-26T14:25:16","slug":"alzheimers-biomarkers-linked-with-plasma-leptin-levels","status":"publish","type":"post","link":"https:\/\/www.drknowhk.org\/mo\/alzheimers-biomarkers-linked-with-plasma-leptin-levels\/","title":{"rendered":"Alzheimer&#8217;s Biomarkers Linked With Plasma Leptin Levels"},"content":{"rendered":"<p class=\"qtranxs-available-languages-message qtranxs-available-languages-message-mo\">\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bc<a href=\"https:\/\/www.drknowhk.org\/en\/wp-json\/wp\/v2\/posts\/12829\" class=\"qtranxs-available-language-link qtranxs-available-language-link-en\" title=\"English\">English<\/a>\u3002<\/p><p>by Judy George<\/p>\n<p>Source Medpagetoday<\/p>\n<div class=\"mpt-key-takeaways-container open\" data-collaspeable-content=\"false\">\n<h4 class=\"mpt-key-takeaways-header\">Key Takeaways<\/h4>\n<div class=\"mpt-key-takeaways-content\">\n<ul>\n<li>Plasma leptin levels were linked with Alzheimer&#8217;s disease PET pathology in cognitively unimpaired older adults in Korea.<\/li>\n<li>Lower baseline leptin was associated with a greater increase in tau over 2 years, while leptin and beta-amyloid showed a cross-sectional association.<\/li>\n<li>While mechanistic pathways are unknown, leptin may be protective against Alzheimer&#8217;s pathology, the researchers suggested.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>Plasma leptin levels were linked with Alzheimer&#8217;s disease PET pathology in cognitively unimpaired older adults, a longitudinal cohort study in Korea showed.<\/p>\n<p>Over 2 years, lower baseline plasma leptin was associated with a greater increase in regional tau (\u03b2 = \u22120.06, 95% CI \u22120.11 to \u22120.01, <em>P<\/em>=0.03), reported Dong Young Lee, MD, PhD, of the Seoul National University College of Medicine.<\/p>\n<p>Read more<a href=\"https:\/\/www.medpagetoday.com\/neurology\/alzheimersdisease\/109964\"> https:\/\/www.medpagetoday.com\/neurology\/alzheimersdisease\/109964<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5c0d\u4e0d\u8d77\uff0c\u6b64\u5185\u5bb9\u53ea\u9069\u7528\u65bcEnglish\u3002by Judy George Source Medpagetoday Key Takeaways Plasma leptin levels were linked with Alzheimer&#8217;s disease PET pathology in cognitively unimpaired older adults in Korea. Lower baseline leptin was associated with a greater increase in tau over 2 years, while leptin and beta-amyloid showed a cross-sectional association. While mechanistic pathways are unknown, leptin may be protective [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":12830,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[49],"tags":[],"class_list":["post-12829","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-brain-cancer-metabolic-syndrome-og"],"_links":{"self":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/12829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=12829"}],"version-history":[{"count":1,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/12829\/revisions"}],"predecessor-version":[{"id":12831,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/12829\/revisions\/12831"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media\/12830"}],"wp:attachment":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=12829"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=12829"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=12829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}