{"id":5301,"date":"2022-01-15T14:36:28","date_gmt":"2022-01-15T14:36:28","guid":{"rendered":"http:\/\/www.drknowhk.org\/?p=5301"},"modified":"2024-03-13T08:19:32","modified_gmt":"2024-03-13T08:19:32","slug":"%e4%b8%ad%e6%96%87-potential-targets-for-treatment-of-coronavirus-disease-2019-covid-19-a-review-of-qing-fei-pai-du-tang-and-its-major-herbs","status":"publish","type":"post","link":"https:\/\/www.drknowhk.org\/mo\/%e4%b8%ad%e6%96%87-potential-targets-for-treatment-of-coronavirus-disease-2019-covid-19-a-review-of-qing-fei-pai-du-tang-and-its-major-herbs\/","title":{"rendered":"Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-8481\" src=\"http:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/03\/AE705DD1-B5DA-433F-A0CD-2101D0A7075C-300x182-1.png\" alt=\"\" width=\"300\" height=\"182\" \/><br \/>\n\u985e\u578b: PDF<br \/>\n\u4f5c\u8005: Linda Li Dan Zhong, Wai Ching Lam, Wei Yang, Kam Wa Chan, Stephen Cho Wing Sze, Jiangxia Miao, Ken Kin Lam Yung, Zhaoxiang Bian, and Vivian Taam Wong<br \/>\n\u51fa\u8655: AJCM<br \/>\n\u9023\u7d50: <a href=\"N\/A\">N\/A<\/a><br \/>\n\u9644\u4ef6: <a href=\"http:\/\/www.drknowhk.org\/wp-content\/uploads\/2024\/03\/Potential-Targets-for-Treatment-of-Coronavirus-Disease-2019-COVID-19-A-Review-of-Qing-Fei-Pai-Du-Tang-and-Its-Major-Herbs.pdf\">PDF\u6587\u4ef6<\/a><br \/>\n<\/p>","protected":false},"excerpt":{"rendered":"<p>It has been recommended in the 6th and 7th versions of Clinical Practice Guideline on COVID-19 in China. The basic scientific studies, supported by network pharmacology, on the possible therapeutic targets of QFPDT and its constituent herbs including Ephedra sinica, Bupleurum chinense, Pogostemon cablin, Cinnamomum cassia, Scutellaria baicalensis were reviewed. The anti-oxidation, immuno-modulation and antiviral mechanisms through dif- ferent pathways were collated. Two clusters of actions identified were cytokine storm pre- vention and angiotensin converting enzyme 2 (ACE2) receptor binding regulation. The multi-target mechanisms of QFPDT for treating viral infection in general and COVID-19 in particular were validated. While large scale clinical studies on QFPDT are being conducted in China, one should use real world data for exploration of integrative treatment with in- clusion of pharmacokinetic, pharmacodynamic and herb-drug interaction studies.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[45],"tags":[],"class_list":["post-5301","post","type-post","status-publish","format-standard","hentry","category-chinese-and-western-therapeutic-pharmacological-research"],"_links":{"self":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/5301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/comments?post=5301"}],"version-history":[{"count":1,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/5301\/revisions"}],"predecessor-version":[{"id":5302,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/posts\/5301\/revisions\/5302"}],"wp:attachment":[{"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/media?parent=5301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/categories?post=5301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.drknowhk.org\/mo\/wp-json\/wp\/v2\/tags?post=5301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}